Thursday, February 10, 2011

Producing Heparin in 100 KG vats

In 2008, adulterated Heparin entered the United States from China.  The New York Times reported 19 deaths, but the importer, Baxter Pharmaceutical claimed a lower figure.  As I type, I am resting after an injection of 8000 units of Heparin. Scientific Protein Labs (SPL) in Changzhou, China was found to have adulterated their heparin with a sulphated derivative of Chondroitin sulfate, which is sold as a food supplement.  SPL never explained why  they adulterate a derivative of pig intestines with a derivative of pig cartilage.  In their report, the FDA also noted that:
On April 21, 2008, after many weeks of intensive investigation and laboratory analysis, we were able to establish a link between a contaminant found in heparin, oversulfated chondroitin sulfate, and the serious adverse events seen in patients given heparin. We have been able to trace the contaminant to 12 different Chinese companies and it has been found in heparin batches shipped to 11 countries.
YIKES!  The FDA tied this to twelve different suppliers and the only named one.  When Baxter Pharmaceutical  lost is market share, the big winner was APP Pharmaceutical.  They are in fact the supplier of my Heparin.  Where does it come from?  To quote them, "Raw materials are from China, which is where all heparin manufacturers receive their raw materials".

So, I am paying Chinese suppliers for extract of pig intestines that they will willingly adulterate, even knowing that this will be injected into human blood.  Am I the only one who finds this unacceptable?  I live in Iowa, which has a population of 18 million pigs.  Why can't we add Heparin processing to slaughterhouses in Iowa? In fact, in United States Patent US6232093, Van Houdenhoven and co-workers describe just how to do this in a patent filing from 2001.  This is a quite readable patent that you can read here online. So, what would it take to get a US slaughterhouse to produce a Heparin extract?  Is Bag Pharma happy with the law suites that result from suppliers that intentionally adulterate their raw materials?

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